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Oklahoma Football vs. Iowa State | Key Storylines

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The Sooners opened up conference play on the road last week, now it’s time for the last ever Big 12 home opener. Oklahoma currently sits as a 20-point favorite over Iowa State, with ESPN’s matchup predictor giving them a 94.3% chance of winning. The Cyclones have only won three times against OU since the 1961 season, two of those were in 2017 and again in 2020. ISU hasn’t been intimidated in Norman in recent trips. Oklahoma has outscored the Cyclone 101-100 over the last three meetings in Norman.

Here are a few more storylines that might be of interest heading into Saturday night.

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