NFL Best Bet For September 17, 2023 | 49ers vs. Rams

Both of our pick sets involve teams from San Francisco playing on the road. We’ve got the Giants at Colorado with our MLB picks, and we’re looking at the 49ers 1-0 vs. the Rams 1-0 for our NFL picks. It hasn’t been a great week all around for us, but NFL on Sunday is a great way to close things out.

The Odds

49ers -7.5

49ers -350 on the moneyline

O/U 45

Why We’re Taking The Rams At +7.5

The season is still very young and there’s still a lot to discover about each team in the league. What we think we know about both of the teams after Week 1 is that they’re solid on offense and stingy on defense. Both teams exploded for 30-plus points last week, and both will face a better defense this week. I like the Rams to lose this one by a touchdown or less, which puts us within that 7.5 point window that we’ve got.

Why We’re Taking The 49ers On The Moneyline

This is a divisional game in just the second week of the season. It’s incredibly important to both squads, so I believe it’ll be a fight all the way to the final snap. San Francisco has a slight edge with the skill position players and I think that tilts them slightly over a Rams team who is nearly equally as talented on the offensive side of the ball. This one should be fun!

Why We’re Taking The Under At 45 Points

I probably haven’t spent enough time talking about the defenses. They’ll both find areas of success against these potent offenses. I think we’re going to be in the neighborhood of a 41-point finish, which gives us just a little cushion before we exceed the 45 points.

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