The Sooners are gunning for their third consecutive one-loss regular season and the Cowboys are looking for a fifth consecutive win this season to stay on pace for a 10-win season.
Here are ten thing you’ll want to know about Saturday night’s game.
10. The Series
Saturday will mark OU’s 114th all-time meeting against OSU, tying the 114 games against Texas for the Sooners’ most versus any program.
The Sooners own an 88-18-7 (.808) all-time record against Oklahoma State, and is 40-7-5 (.817) in the series in Stillwater. OU has won 14 of the last 16 meetings and is 12-2 against OSU with Mike Gundy as the Cowboys’ head coach.
OU’s 88 wins against Oklahoma State are its most against one opponent and the second most in FBS history against one program (Nebraska has 91 wins vs. Kansas).
The Sooners’ 40 wins in Stillwater are their most on the road versus an opponent. They have won seven of their last eight at Boone Pickens Stadium and since 1936 are 34-4-2 (.875) in Stillwater.
This marks the 12th time in the last 15 years for OU and OSU to meet in the final game of the regular season.
9. The Streak
Oklahoma State has won each of its past four games to mark its longest win streak this year. The Cowboys are 8-3 on the season, marking the 10th time in the past 12 years the Cowboys have won at least eight games.
8. Close To Making History
Oklahoma leads the Big 12 in total offense (574.7 ypg) and total defense (336.2 ypg). The Sooners have never accomplished that feat in a full season.
7. The Heisman Candidates
Oklahoma State running back Chuba Hubbard leads the nation in nearly every statistical rushing category, including rushing yards, rushing yards per game, all-purpose yards, yards after contact (via Pro Football Focus) and more. His average of 166.5 rushing yards per game is 13.3 more than second-place Jonathan Taylor of Wisconsin. Hubbard’s rushing yards through 11 games are better than six of the 12 running backs to win the Heisman Trophy since 1980.
Oklahoma quarterback Jalen Hurts leads the conference in total offense (394.5 ypg; next most is 349.4) and pass efficiency rating (203.1; next highest is 156.2; FBS record is 199.4), and ranks second in passing yards (289.5) and rushing yards (105.1; second most nationally among QBs) per game.
Hurts is only the third FBS player to register at least 3,000 passing yards and 1,000 rushing yards by the 11th game of a season. The feat was also accomplished by Louisville’s Lamar Jackson in 2016 and ’17 and Texas A&M’s Johnny Manziel in 2012 (Jackson  and Manziel won the Heisman Trophy).
6. The Defenses
The Cowboys have put together their best performances over the past four games, forcing 10 turnovers and holding opponents to an average of 20 points per game. Safety Kolby Harvell-Peel has made his case for All-America honors, ranking No. 3 in the FBS in passes defended and No. 5 in the FBS with five interceptions this season. On top of that, he set an OSU single-game record with six pass breakups at Iowa State, which also ties for the highest single-game total of any player in the FBS.
In Big 12 play, OU leads the league in total defense (330.0 ypg) and passing defense (188.4 ypg), and ranks second in pass defense efficiency (126.9 rating) and third in rushing defense (141.6 ypg) and sacks (2.4 per game).
5. Home On The Road
Oklahoma has won 23 of its last 24 true road games, with the only loss during that stretch coming at Kansas State on Oct. 26. OU had a 22-game true road winning streak (it hadn’t lost since Oct 4, 2014) come to an end Oct. 26 at Kansas State (48-41). It was the second longest such streak nationally since at least the end of World War II (the Sooners also won 25 straight from 1953 to 58).
4. Taking On The Top 25
Oklahoma State is 8-3 in its last 11 games against teams ranked in the Associated Press top 25 and already has two such wins this season. Since 2013, Oklahoma State has beaten five teams ranked in the top 10 of the AP poll inside Boone Pickens Stadium.
3. Cover #2
Consensus first-team midseason All-American and Biletnikoff Award Finalist CeeDee Lamb is continuing his rapid ascent on OU’s charts this season. The junior wide receiver from Richmond, Texas, who was also a Maxwell Award semifinalist, ranks second in career receiving touchdowns (32), fourth in receiving yards (2,964) and is tied for ninth in receptions (157) despite playing in just his third season.
In 10 games this season (he missed the Nov. 16 contest at Baylor due to medical reasons), Lamb has posted team highs of 46 catches, 999 receiving yards and 14 receiving touchdowns. He ranks third nationally in receiving TDs and yards per reception (22.3) and 13th in receiving yards per game (99.9).
2. The Turnover Factor
Since 2005, when the Cowboys win the turnover battle they are 70-9 (88.6 pct.). They are 37-2 (94.9 pct.) in games when they commit zero turnovers.
1. Doing What They Do Best
Oklahoma led the nation last season in both yards per pass attempt (11.3) and yards per rush (6.6). This year, it ranks first nationally (min. 10 attempts per game) with its 11.4 yards per pass attempt (FBS record is 11.7 by OU in 2017) and ranks third with its 6.4 yards per rush (school record is 7.1 in 1971).
The Sooners are averaging a national-best 8.44 yards per play, which is just below their own FBS single-season record of 8.60 yards per play set last season.
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